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Fantasy Football Start ‘Em, Sit ‘Em QB Picks for Week 15 Include Brock Purdy, Jared Goff, and Jacoby Brissett thumbnail

Fantasy Football Start ‘Em, Sit ‘Em QB Picks for Week 15 Include Brock Purdy, Jared Goff, and Jacoby Brissett

Fantasy football is all about timing and knowing when to trust the hot hand and when to pivot before the points dry up. This week’s slate offers several intriguing quarterback matchups with more risk than they might seem on paper.

Some have everything lining up for a breakout, while others face defenses that could quickly turn optimism into regret. Let’s sort through which signal-callers deserve a start and who’s better left on the bench.

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Check out the FREE Start/Sit Optimizer from PFSN to ensure you are making the right decisions for your fantasy lineup every week!

Start ‘Em: Brock Purdy, QB, San Francisco 49ers (vs. TEN)

Whenever you start a quarterback on a run-first offense, there’s always the risk that the running backs steal all the touchdowns. If that happens, so be it. Still, we can’t discount the tremendous opportunity in front of Brock Purdy this week.

The San Francisco 49ers are well rested coming off their bye. As a reward, they get a home date with a Tennessee Titans defense that just gave up 364 yards and four total touchdowns to Shedeur Sanders.

The Titans allow the ninth-most fantasy points per game to quarterbacks. Yes, likely, this game is over after three quarters, limiting what Purdy needs to do in the fourth quarter. But the 49ers still have to get to the point where the game is decided. They are probably good for at least four touchdowns in this one. Christian McCaffrey can’t run for all of them.

Jared Goff, QB, Detroit Lions (at LAR)

It’s always risky recommending Jared Goff on the road. However, I do think the Road Goff/Home Goff splits are a bit misconstrued. It’s really more of an issue with Dome Goff and Outside Goff. That won’t be an issue this week.

The Detroit Lions are coming off a decisive win against the Dallas Cowboys. They scored 44 points. Yet, Goff only managed one touchdown pass thanks to Jahmyr Gibbs and David Montgomery hogging the other four. That is scoring randomness and something we cannot account for

The Los Angeles Rams have a great defense. However, they are much more vulnerable in the air than on the ground. Plus, they are likely to force the Lions into a negative game script, something the Cowboys could not do. The hope here is that we get a good old-fashioned shootout.

Goff has thrown a touchdown in every game this season, giving him a solid floor. Given how stout the Rams are against the run, hopefully, the Lions lean on the pass when they get closer to the goal line, putting Goff firmly in the QB1 ranks.

Sit ‘Em: Jacoby Brissett, QB, Arizona Cardinals (at HOU)

Somehow, every week, Jacoby Brissett gets there. Even in the extreme negative game script last week, Brissett managed to reach 20 fantasy points. He’s now hit 18+ fantasy points in every start this season. Regardless of the matchup, Brissett finds a way.

This is not exactly a bold claim, but the run will end this week. Or, at least, go on pause for a game.

No one gets through on the Houston Texans. No one. Not Josh Allen. Not Patrick Mahomes. And certainly not Brissett.

The Texans are the No. 1 defense in football. No team allows fewer fantasy points per game to quarterbacks. They are the only team this season to have not allowed a single QB1 performance. The aforementioned Allen and Mahomes couldn’t even get to double digits.

Brissett is poised to resume carrying fantasy teams in Weeks 16 and 17. But for Week 15, find someone else.

Bo Nix, QB, Denver Broncos (vs. GB)

Last week against the Raiders, the Broncos leaned heavily on RJ Harvey. That led to Bo Nix throwing for 212 scoreless yards. If not for his first rushing touchdown since Week 7, Nix might have finished in the single digits.

This game between the Broncos and Packers projects to be a low-scoring, defensive slog. These are two excellent defenses with offenses that want to run the ball.

Green Bay allows the fewest fantasy points per game to quarterbacks. All of Nix’s highly productive fantasy outings have come against bottom-of-the-barrel pass defenses. He will enjoy no such thing in this week’s matchup.

Fantasy Football Week 15 QB Takeaways

Fantasy football decisions often come down to balancing risk and reward, and this week’s quarterbacks highlight that perfectly. Purdy and Goff both have strong cases to deliver at home and on the road, respectively, given the offensive talent around them and favorable situations.

On the flip side, Brissett and Nix face uphill battles against top-tier defenses that could easily limit their upside. As the fantasy playoffs approach, every lineup choice matters more than ever. Trust the matchups, stick with your process, and keep chasing the points that push you closer to a championship.

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